The Springboks opened their campaign in fine style, beating the All Blacks 26-10 at the Mbombela Stadium, Nelspruit.
The Pumas started well in Mendoza but Wallabies score five tries to win well.
Springboks host the All Blacks in Nespruit in Round 1 with both eager to get the season off to a winning start.
Former Wallabies coach Michael Cheika has Los Pumas primed in Mendoza.
Approval of 20-minute Red Card Law Trial in The Rugby Championship 2022.
Los Pumas get several big names back for their two home TRC matches against the Wallabies.
The Emirates World Rugby match officials have been appointed for The Rugby Championship 2022, which runs from 6 August to 24 September.
Wallabies coach Dave Rennie has confirmed a 36-man squad that will tour Argentina for the opening two matches of the 2022 Rugby Championship.
The Springboks clinched a hard-fought 2-1 series win over Wales beating their determined opponents by 30-14 in the third test.
The Pumas scored an 81st-minute try to beat Scotland 34-31 in the third Test to claim the series 2-1.
Ireland make history with 32-22 win against All Blacks for first ever series win in New Zealand.
England have won the Ella-Mobbs Cup after a 21-17 victory over the Wallabies at the SCG.
The Pumas and Scotland have pressed the reset button by making wholesale changes for the Third Test in Santiago.
Reds backrower Harry Wilson and Melbourne fullback Reece Hodge both selected for the decider in Sydney.
The All Blacks have made several changes to the matchday squad after the Second Test loss to Ireland.
Springbok coach Jacques Nienaber made 11 changes to his starting lineup for the Series decider against Wales in Cape Town.
Scotland levelled their series 1-1 against Argentina with a strong 29-6 victory in Salta.
England have levelled the series after a 25-17 win over Australia at Suncorp Stadium.
Ireland claimed a famous win beating the All Blacks 23-12 in Dunedin.
Wales have made history by beating the Springboks in South Africa for the first time.