The Hemisphere Shield has been revealed as the prize that will immortalise Northern or Southern Hemisphere supremacy.
The Wallabies drew 28-all with Los Pumas in the second test but take the series 1-0.
Tom Wright will bring up his 50th cap for Australia being named to start at fullback against Argentina.
The Pumas will be out for revenge in their last home test of the year against the Wallabies in Mendoza.
The Wallabies have continued their strong start to the Les Kiss era with a tough win over Los Pumas 27-21.
Wallabies prop Allan Alaalatoa has been named captain as coach Kiss names team to face Argentina in Salvador de Jujuy.
Los Pumas Coach Contepomi sticks with the tried and tested for Wallabies Test after previous loss to Springboks.
The Nations Championship Finals Weekend will determine the dominant rugby hemisphere in international rugby.
The Springboks recorded a 12th successive victory but had to overcome a feisty Pumas to record a 17-10 victory in Buenos Aires.
Seven yellow cards and a disallowed try, that could have drawn the match for hosts, highlight England's 31-24 win over Pumas.
Contepomi makes slight adjustments to Pumas who face an unchanged England team in Santiago del Estero.
It will be the first time these sides, the U20 Six Nations and U20 Rugby Championship winners, will meet in the Junior World Championship final.
In the second round of the Nations Championship, Los Pumas beat Wales 35-21 at the San Juan del Bicentenario Stadium.
Head coach Felipe Contepomi has made five changes to the starting XV for the Wales match after the loss to Scotland.
England to face defending champions South Africa and France clinch New Zealand showdown as two huge semi-finals are confirmed after the pool stage in Georgia.
After two rounds South Africa, New Zealand, Argentina and Australia all top their pools with RD3 determining the knockout matches.
In the opening round of the Nations Championship, Los Pumas fell to Scotland 47-38 at the Mario Alberto Kempes Stadium in Cordoba.
Defending champions South Africa, New Zealand, Argentina and Australia sit top of their respective pools.
The Pumas face Scotland followng last November's win where they came back from 0-21 down to win the match 33-24 at Murrayfield in Edinburgh
After big wins in the first round Australia and Argentina will be out to secure a second World Chmapionship victory in Georgia.