There are four changes to the starting XV that suffered a defeat to Wales in Cardiff last weekend.
The Pumas are bolstered by the return of their captain Julian Montoya.
He missed the match in Cardiff because of a rib injury and he will replace Agustin Creevy, who drops out of the matchday 23.
The other change in the front row sees Eduardo Bello come in for Francisco Gomez Kodela.
There is a change in the midfield with Matias Orlando taking over the No.13 jersey from Matias Moroni.
The final change is on the wing where Bautista Delguy gets an opportunity ahead of Mateo Carreras.
Meanwhile, the Pumas will also be bolstered by the return of veteran flyhalf Nicolas Sanchez [pictured below], who will be playing off the bench.
Argentina:
15 Juan Cruz Mallia
14 Bautista Delguy
13 Matias Orlando
12 Jeronimo de la Fuente
11 Emiliano Boffelli
10 Santiago Carreras
9 Gonzalo Bertranou
8 Pablo Matera (captain)
7 Marcos Kremer
6 Juan Martin Gonzalez
5 Tomas Lavanini
4 Matias Alemanno
3 Eduardo Bello
2 Julian Montoya
1 Thomas Gallo.
Replacements:
16 Ignacio Ruiz
17 Nahuel Tetaz Chaparro
18 Santiago Medrano
19 Lucas Paulos
20 Facundo Isa
21 Lautaro Velez-Bazan
22 Nicolas Sanchez
23 Matías Moroni.
