The Pumas are seeking an unprecedented third victory in this year's TRC while the Wallabies are desperate to find some winning form.
The All Blacks have won the title but Springboks would love to finish with same number of wins as their arch rivals.
Australia will look for an improved defensive display this weekend and Michael Hoper and David Pocock will again lead the charge.
Springbok Aphiwe Dyantyi and All Black Rieko Ioane are two of the world's best young wingers and go head-to-head in Pretoria.
South Africa continued with their fine recent form when they beat Australia 23-12 in the Round 5 Rugby Championship Test in Port Elizabeth.
New Zealand wrapped up a third successive Rugby Championship title on Saturday after they beat Argentina 35-17 at Estadio Jose Amalfitani.
The All Blacks team has been named to play the Pumas in Round 5 of TRC at in Buenos Aires, who themselves have made two changes to their lineup.
Cheslin Kolbe and Sikhumbuzo Notshe will make their run-on debuts for the Springboks against the Wallabies in Port Elizabeth on Saturday.
Wallabies coach Michael Cheika has made four changes to his starting fifteen ahead of Australia’s Round 5 TRC Test against South Africa in Port Elizabeth on Saturday.
The Pumas wingers Bautista Delguy and Ramiro Moyano have been key to the success of the revitalised team this season under coach Mario Ledesma.
All Black Ben Smith is one of the world's best outside backs comfortable at wing, fullback or wherever his coach puts him but what is his best position?
Wallabies coach Michael Cheika has named two uncapped players in his 30-man squad to tour South Africa and Argentina for the last two matches of The Rugby Championship.
Springbok coach Rassie Erasmus has added several players to his squad for the Rugby Championship matches against Australia and New Zealand.
Argentina returned to winning ways in the Rugby Championship when they claimed a hard-fought 23-19 win over Australia on the Gold Coast on Saturday.
South Africa sensationally upset the All Blacks 36-34 in Wellington to win in New Zealand for first time since 2009.
Wallabies captain Michael Hooper has been withdrawn from the match while David Pocock and Israel Folau have been named to make their return for the Test against Argentina on the Gold Coast.
Springbok coach Rassie Erasmus tweaks starting line-up for All Black Test in Wellington.
All Blacks coach Steve Hansen brings back his experienced test players for the match against South Africa in Wellington.
Few players have done more for the game of rugby in Argentina than Nicolas Sanchez and his team will look to him as the inspiration for victory against Australia on the Gold Coast.
The All Blacks again lead the way in this year's Rugby Championship and their success is backed up by impressive figures that show they lead the way in most game statistics.