The Pumas are seeking an unprecedented third victory in this year's TRC while the Wallabies are desperate to find some winning form.
New Zealand wrapped up a third successive Rugby Championship title on Saturday after they beat Argentina 35-17 at Estadio Jose Amalfitani.
The All Blacks team has been named to play the Pumas in Round 5 of TRC at in Buenos Aires, who themselves have made two changes to their lineup.
The Pumas wingers Bautista Delguy and Ramiro Moyano have been key to the success of the revitalised team this season under coach Mario Ledesma.
Argentina returned to winning ways in the Rugby Championship when they claimed a hard-fought 23-19 win over Australia on the Gold Coast on Saturday.
Wallabies captain Michael Hooper has been withdrawn from the match while David Pocock and Israel Folau have been named to make their return for the Test against Argentina on the Gold Coast.
Few players have done more for the game of rugby in Argentina than Nicolas Sanchez and his team will look to him as the inspiration for victory against Australia on the Gold Coast.
New Zealand retained their unbeaten status in this year’s Rugby Championship when they claimed a 46-24 win over Argentina in Nelson in Round 3.
All Blacks' coach Steve Hansen has made several changes to the side for the Test against Argentina in Nelson with Richie Mo'unga getting his first start.
Pumas coach Mario Ledesma has made four changes to the team that will play the All Blacks in Nelson in Round 3 of The Rugby Championship.
Argentina ended an eleven-match losing streak in the Rugby Championship when they claimed a deserved 32-19 win over South Africa in Mendoza on Saturday.
The Springboks travel to Mendoza to face Los Pumas with one change to the starting lineup while Ledesma shuffles the Pumas bench.
Is there such a thing as a talisman? Do teams struggle in the absence of key players?
The Springboks opened their Rugby Championship account with a 34-21 come-from-behind victory over Argentina at Kings Park in Durban on Saturday.
Super Rugby is done and dusted and now attention focuses on the Rugby Championship as the national coaches announce their extended straining squads.
Super Rugby took a break in June due to the international test window - here is a review of the action and the players who stood out ahead of The Rugby Championship later this year...
Argentina's poor June continued in Resistencia with a 15-44 loss to Scotland following recent losses to Wales.
A young Wales team defied the odds to record a stunning 23-10 victory over Argentina in San Juan.
Wallabies coach Michael Cheika has confirmed his squad for the blockbuster three-Test Ireland Series that kicks off at Suncorp Stadium on Saturday 9 June.
Ireland claimed their third win in three November Tests with a clinical 28-19 victory over Argentina at the Aviva Stadium in Dublin.