Rohan Janse van Rensburg, Jamba Ulengo and Uzair Cassiem will make their Springbok debuts against Wales in Cardiff while a fourth uncapped player, Jean-Luc du Preez, has been included on the bench for the final match of the November Tour.
The Wallabies showed their mettle to overcome a spirited French outfit 25-23 in a nailbiting match at Stade de France. David Pocock, leading the Wallabies as captain was instrumental forcing crucial turnovers and halting the French attack with his brick-wall defence.
Record try-scorer Bryan Habana is back at left wing for the Springboks when they face Italy in Florence on Saturday, while Nizaam Carr will get his first start for South Africa against the same opponents he made his Test debut against two years ago.
The All Blacks team has been named to play Ireland in the eagerly-anticipated Test at Aviva Stadium, Dublin. The Irish won the last encounter in Chicago two weeks ago thus ending the All Blacks world record Test run.